Minocycline intravenous - Melinta Therapeutics

Drug Profile

Minocycline intravenous - Melinta Therapeutics

Alternative Names: Minocin; Minocin IV; Minocin® for Injection; Minocycline hydrochloride - The Medicines Company; RPX 602

Latest Information Update: 17 Jul 2018

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At a glance

  • Originator Rempex Pharmaceuticals
  • Developer Rempex Pharmaceuticals; The Medicines Company
  • Class Amides; Anti-inflammatories; Antiacnes; Antibacterials; Dimethylamines; Neuroprotectants; Skin disorder therapies; Small molecules; Tetracyclines
  • Mechanism of Action Glial cell inhibitors; Interleukin 1 alpha inhibitors; Interleukin-6 modulators; Protein 30S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Gram-negative infections; Gram-positive infections

Most Recent Events

  • 04 Jun 2018 Rempex terminates a phase I trial in Gram-negative and Gram-positive infections (In volunteers) in Germany due to change in strategy (IV) (NCT02808052)
  • 08 Feb 2018 Rempex Pharmaceuticals completes a phase I trial in Gram-negative and Gram-positive infections (In volunteers) in Netherlands (IV) (NCT02802631)
  • 08 Jan 2018 Melinta Therapeutics acquires Minocycline intravenous from The Medicines Company
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