Drug Profile

Research programme: MTAP-deleted cancer therapeutics - Agios/Celgene

Alternative Names: PRMT5 inhibitor - Bristol Myers Squibb

Latest Information Update: 28 May 2025

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At a glance

Originator Agios Pharmaceuticals
Class Antineoplastics; Small molecules
Mechanism of Action PRMT5 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Solid tumours

Most Recent Events

28 May 2025 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
10 Apr 2021 Preclinical trials in Cancer in USA (Parenteral) before April 2021
10 Apr 2021 Pharmacodynamics data from a preclinical trial in cancer presented at the 112th Annual Meeting of the American Association for Cancer Research (AACR-2021)

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