Research programme: MTAP-deleted cancer therapeutics - Agios/Celgene

Drug Profile

Research programme: MTAP-deleted cancer therapeutics - Agios/Celgene

Latest Information Update: 20 Mar 2018

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At a glance

  • Originator Agios Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Protein-arginine N-methyltransferase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Research Cancer

Most Recent Events

  • 14 Feb 2018 Agios Pharmaceuticals has pending patents for MTAP-deleted cancer therapeutics in countries worldwide
  • 26 Dec 2017 Agios Pharmaceuticals plans a dose-escalation phase I trial of AG 270 for MTAP-deleted Cancer (Late-stage disease, Second-line therapy or greater) in USA, France and Spain in the first quarter of 2018 (PO) (NCT03435250)
  • 04 May 2017 Agios intends to submit IND application for AG 270 to the US FDA for Cancer by the end of 2017
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