Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

MEN 1112

Next Previous
Drug Profile

MEN 1112

Alternative Names: ADC-001; MEN1112; MEN1112/OBT357; OBT357; OX 357; OX-001

Latest Information Update: 03 Aug 2021

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Menarini; Oxford BioTherapeutics
  • Class Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia

Most Recent Events

  • 03 Aug 2021 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in Spain, Germany, Italy, France, Belgium, before August 2021 (IV) (Menarini pipeline, August 2021)
  • 10 Apr 2021 Preclinical trials in Myelodysplastic syndromes in Italy (unspecified route)
  • 10 Apr 2021 Pharmacodynamics data from a preclinical studies in Acute myeloid leukemia presented at the 112th Annual Meeting of the American Association for Cancer Research (AACR-2021)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top