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Brensocatib - Insmed

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Drug Profile

Brensocatib - Insmed

Alternative Names: AZD 7986; INS-1007

Latest Information Update: 14 Jan 2025

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Insmed
  • Class Amides; Anti-inflammatories; Antibronchitics; Benzoxazoles; Nitriles; Oxazepines; Skin disorder therapies; Small molecules
  • Mechanism of Action Dipeptidyl peptidase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Bronchiectasis
  • Phase II Hidradenitis suppurativa; Rhinosinusitis
  • Discontinued Chronic obstructive pulmonary disease; COVID 2019 infections; Cystic fibrosis; Granulomatosis with polyangiitis

Most Recent Events

  • 10 Jan 2025 Insmed anticipates to launch Brensocatib In Bronchiectasis (Non-cystic fibrosis-related) in the US in Q3 2025
  • 31 Dec 2024 Preregistration for Bronchiectasis (In adolescents, In the elderly, In adults, Non-cystic fibrosis-related) in USA (PO)
  • 30 Dec 2024 Phase-II clinical trials in Hidradenitis suppurativa in USA (PO) (NCT06685835)

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