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Recombinant staphylokinase - Supergene

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Drug Profile

Recombinant staphylokinase - Supergene

Alternative Names: Fortelyzin; Forteplase®; Gene modified staphylokinase - Supergene; Recombinant nonimmunogenic staphylokinase - Supergene; Recombinant staphylokinase variant - Supergene

Latest Information Update: 14 Jan 2026

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At a glance

  • Originator Supergene
  • Class Anti-ischaemics; Metalloendopeptidases; Plasminogen activator enzymes; Recombinant proteins; Thrombolytics; Vascular disorder therapies
  • Mechanism of Action Plasminogen activators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Ischaemic stroke; Peripheral arterial occlusive disorders; Pulmonary embolism
  • Phase II/III COVID 2019 infections
  • No development reported Myocardial infarction

Most Recent Events

  • 08 Jan 2026 Supergene plans the phase III FRIDA-CT trial for Ischaemic stroke in Russia in February 2026 (IV) (NCT07324837)
  • 01 Jun 2025 Supergene initiates observational trials in Pulmonary embolism in Russia (IV) (NCT07245927)
  • 23 May 2024 Phase-III clinical trials in Pulmonary embolism in Russia (IV, Injection) (NCT06362746)

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