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Ribaxamase - Theriva Biologics

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Drug Profile

Ribaxamase - Theriva Biologics

Alternative Names: Bacillus licheniformis isoenzyme; Kymerase; P3A; SYN 007; SYN-004 - Theriva Biologics

Latest Information Update: 10 Oct 2024

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At a glance

  • Originator Ipsat Therapies
  • Developer Theriva Biologics
  • Class Aminohydrolases; Antibacterials; Irritable bowel syndrome therapies
  • Mechanism of Action Beta lactamase replacements; Gastrointestinal microbiome modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Clostridium difficile infections
  • Phase I/II Graft-versus-host disease
  • Discontinued Irritable bowel syndrome

Most Recent Events

  • 04 Oct 2024 Theriva Biologics announces positive outcome of data and safety monitoring committee (DSMC) review in Cohort II of phase Ib/IIa trial
  • 04 Oct 2024 Adverse events, pharmacokinetics and efficacy data from a phase I/II trial in Graft-versus-host disease released by Theriva Biologics
  • 16 Apr 2024 Discontinued - Preclinical for Irritable bowel syndrome (Prevention) in USA (unspecified route) before December 2023

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