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Brepocitinib - Priovant Therapeutics

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Drug Profile

Brepocitinib - Priovant Therapeutics

Alternative Names: Brepocitinib tosylate - Pfizer; PF 6700841; PF-06700841; PF-06700841-15; PF-841

Latest Information Update: 27 Sep 2024

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At a glance

  • Originator Pfizer
  • Developer Pfizer; Priovant Therapeutics
  • Class Amides; Anti-inflammatories; Antipsoriatics; Antirheumatics; Arylsulfonic acids; Bridged-ring heterocyclic compounds; Cyclopropanes; Fluorinated hydrocarbons; Ketones; Pyrazoles; Pyrimidines; Skin disorder therapies; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Dermatomyositis; Uveitis
  • Phase II Crohn's disease; Hidradenitis suppurativa
  • Discontinued Alopecia; Alopecia areata; Atopic dermatitis; Lupus vulgaris; Plaque psoriasis; Psoriatic arthritis; Systemic lupus erythematosus; Ulcerative colitis; Vitiligo

Most Recent Events

  • 23 Sep 2024 Phase-III clinical trials in Uveitis in USA (PO) (NCT06431373)
  • 23 Sep 2024 Brepocitinib - Priovant Therapeutics receives Fast Track designation for Uveitis [PO] in USA
  • 23 Sep 2024 Priovant Therapeutics announces intention to submit NDA in Dermatomyositis

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