Ivuxolimab - Pfizer
Alternative Names: anti-OX40R-11D4; B110; OX 40; PF-04518600; PF-8600Latest Information Update: 21 Feb 2025
At a glance
- Originator Pfizer
- Developer Dana-Farber Cancer Institute; M. D. Anderson Cancer Center; National Cancer Institute (USA); Pfizer; University of Southern California
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action OX40 receptor agonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Renal cell carcinoma; Solid tumours; Triple negative breast cancer
- Phase I/II Acute myeloid leukaemia; Squamous cell cancer
- No development reported Follicular lymphoma
Most Recent Events
- 21 Feb 2025 Dana-Farber Cancer Institute terminates a phase Ib trial for Follicular lymphoma (Combination therapy, First-line therapy) in USA (IV) due to drug manufacturer withdrawing supply/funding (NCT03636503)
- 28 Jan 2025 No recent reports of development identified for phase-I development in Follicular lymphoma(Combination therapy, First-line therapy) in USA (IV)
- 28 Jan 2025 No recent reports of development identified for phase-I development in Follicular lymphoma(Combination therapy, Second-line therapy or greater) in USA (IV)