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Voxelotor - Global Blood Therapeutics

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Drug Profile

Voxelotor - Global Blood Therapeutics

Alternative Names: GBT-440; GTx-011; Oxbryta

Latest Information Update: 01 Oct 2024

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At a glance

  • Originator Global Blood Therapeutics
  • Developer Global Blood Therapeutics; Pfizer
  • Class Antianaemics; Antifibrotics; Benzaldehydes; Ethers; Pyrazoles; Pyridines; Small molecules
  • Mechanism of Action Sickle haemoglobin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Sickle cell anaemia
  • Discontinued Hypoxia; Idiopathic pulmonary fibrosis

Most Recent Events

  • 01 Oct 2024 Withdrawn for Sickle cell anaemia (In children, In the elderly, In adults, In adolescents) in United Arab Emirates (PO)
  • 25 Sep 2024 Discontinued - Clinical-Phase-Unknown for Sickle cell anaemia (In the elderly, In adults, In adolescents) in Brazil (PO)
  • 25 Sep 2024 Discontinued - Phase-II for Sickle cell anaemia (In adolescents, In infants) in USA (PO)

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