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NBI 921352

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Drug Profile

NBI 921352

Alternative Names: NBI-921352; XEN 901

Latest Information Update: 25 Apr 2024

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At a glance

  • Originator Xenon Pharmaceuticals
  • Developer Neurocrine Biosciences; Xenon Pharmaceuticals
  • Class Antiepileptic drugs; Small molecules
  • Mechanism of Action Nav1.6 voltage-gated sodium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Epilepsy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Epilepsy
  • Discontinued Dravet syndrome; Seizures

Most Recent Events

  • 12 Apr 2024 Neurocrine Biosciences terminated a phase II long-term extension trial for Seizures (Adjunctive treatment) in Hungary, Australia, Belgium, Czech Republic, France, Italy, and Spain (PO) bcz parent study failed to meet its primary endpoint (NCT05493293)
  • 31 Dec 2023 Xenon Pharmaceuticals has patent protection for NBI 921352 Worldwide
  • 31 Dec 2023 Xenon Pharmaceuticals has patent protection for NBI 921352 in US

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