Research programme: single domain antibody therapeutics - AdAlta

Drug Profile

Research programme: single domain antibody therapeutics - AdAlta

Alternative Names: AD 114; AD-214; i-bodies

Latest Information Update: 27 Feb 2018

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At a glance

  • Originator AdAlta
  • Developer AdAlta; Lonza; University of Sydney
  • Class Antibodies; Antifibrotics; Proteins
  • Mechanism of Action CXCR4 receptor antagonists; G protein-coupled receptor modulators; Ion channel modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Idiopathic pulmonary fibrosis
  • Research Fibrosis; Kidney disorders; Retinal disorders

Most Recent Events

  • 18 Apr 2018 AdAlta plans a phase I trial for Idiopathic pulmonary fibrosis in 2019
  • 21 Feb 2018 AdAlta plans to complete an initial first-in-human study in Idiopathic pulmonary fibrosis (In volunteers), in 2018
  • 19 Feb 2018 AdAlta plans to complete final preclinical toxicology studies for Idiopathic pulmonary fibrosis (IPF) in Australia
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