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18F F AraG - CellSight Technologies

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Drug Profile

18F F AraG - CellSight Technologies

Alternative Names: 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine; 18[F]F-AraG; 18F-AraG; [18F]F-ARAG PET; AraG-18[F]F; F18F-AraG; Flourine-18 labelled arabino furanosyl guanine - CellSight Technologies; Fluorine F 18 Ara-G; VisAcT

Latest Information Update: 22 May 2024

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At a glance

  • Originator Stanford University
  • Developer Boehringer Ingelheim; CellSight Technologies; Checkmate Pharmaceuticals; Stanford University; University of California at San Francisco; University of Pittsburgh
  • Class Arabinonucleosides; Furans; Imaging agents; Purines; Radiopharmaceutical diagnostics; Small molecules
  • Mechanism of Action Positron-emission tomography enhancers; Radionuclide imaging enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Malignant melanoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Solid tumours
  • No development reported Bladder cancer; Cancer; COVID 2019 infections; Head and neck cancer; HIV infections

Most Recent Events

  • 16 May 2024 M.D. Anderson Cancer Center plans a phase 0 trial for Oesophageal cancer (Diagnosis) in USA (IV, Injection) (NCT06414902)
  • 28 Apr 2024 No recent reports of development identified for phase-I development in COVID-2019-infections(Diagnosis, In the elderly, In adults) in USA (IV)
  • 13 Feb 2024 University of Pittsburgh, in collaboration with Checkmate Pharmaceuticals and CellSight Technologies suspends a phase II trial in Malignant melanoma (Late-stage disease, Combination therapy, Neoadjuvant therapy) in USA (IV) due to evaluation in process, and pending new trial with similar agents (NCT04401995)
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