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Navicixizumab - Mereo BioPharma/OncXerna Therapeutics

Drug Profile

Navicixizumab - Mereo BioPharma/OncXerna Therapeutics

Alternative Names: anti-DLL4/VEGF bispecific antibody - Mereo BioPharma/OncXerna Therapeutics; OMP 305B83

Latest Information Update: 28 Jan 2023

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At a glance

  • Originator OncoMed Pharmaceuticals
  • Developer OncoMed Pharmaceuticals; OncXerna Therapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action DLL4 protein inhibitors; Stem cell modulators; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Breast cancer; Colorectal cancer; Fallopian tube cancer; Gastric cancer; Ovarian cancer; Peritoneal cancer
  • No development reported Solid tumours

Most Recent Events

  • 28 Jan 2023 No recent reports of development identified for phase-I development in Fallopian-tube-cancer(Combination therapy, Second-line therapy or greater) in USA (IV, Infusion)
  • 28 Jan 2023 No recent reports of development identified for phase-I development in Ovarian-cancer(Combination therapy, Second-line therapy or greater) in USA (IV, Infusion)
  • 28 Jan 2023 No recent reports of development identified for phase-I development in Peritoneal-cancer(Combination therapy, Second-line therapy or greater) in USA (IV, Infusion)
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