Evobrutinib - Merck Serono

Drug Profile

Evobrutinib - Merck Serono

Alternative Names: M-2951; MSC 2364447; MSC2364447C

Latest Information Update: 09 Apr 2018

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At a glance

  • Originator Merck Serono
  • Class Antirheumatics; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Rheumatoid arthritis; Systemic lupus erythematosus
  • Phase I Autoimmune disorders
  • Preclinical Encephalomyelitis

Most Recent Events

  • 21 Mar 2018 Merck KGaA initiates enrolment in a phase I trial in volunteers in Germany (NCT03436394)
  • 07 Mar 2018 Evobrutinib is still in phase I trials for Autoimmune-disorders (In volunteers) in Germany
  • 28 Feb 2018 No recent reports of development identified for phase-I development in Autoimmune-disorders(In volunteers) in Germany (PO)
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