Adafosbuvir - Alios BioPharma

Drug Profile

Adafosbuvir - Alios BioPharma

Alternative Names: AL335; ALS-335; JNJ-64146212

Latest Information Update: 30 Jan 2018

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At a glance

  • Originator Alios BioPharma
  • Developer Alios BioPharma; Janssen
  • Class Antivirals; Pyrimidine nucleotides; Uracil nucleotides
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis C

Most Recent Events

  • 30 Jan 2018 Chemical structure information added
  • 27 Oct 2017 Janssen completes a phase I cardiac safety trial in Healthy volunteers in USA (NCT03155893)
  • 14 Sep 2017 Janssen plans a phase I trial in Healthy volunteers (Monotherapy, Combination therapy) in USA (NCT03277755)
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