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ARB 1467

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Drug Profile

ARB 1467

Alternative Names: ARB 1468; ARB-001467; ARB-1467; TKM HBV

Latest Information Update: 27 Mar 2019

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At a glance

  • Originator Protiva Biotherapeutics
  • Developer Arbutus Biopharma
  • Class Antivirals; Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis B

Most Recent Events

  • 07 Mar 2019 Arbutus Biopharma terminates a phase II trial in Hepatitis B (Combination therapy) in Poland and Spain as the company discontinued the development of the drug and to focus on the development of next-generation RNAi agent AB 729 (IV) (EudraCT2017-001647-12)
  • 31 Dec 2018 Discontinued - Phase-II for Hepatitis B (Combination therapy) in Poland (IV)
  • 31 Dec 2018 Discontinued - Phase-I for Hepatitis B (In volunteers) in Canada (IV)

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