Research programme - kinase-inhibiting RNase attenuators - OptiKira

Drug Profile

Research programme - kinase-inhibiting RNase attenuators - OptiKira

Alternative Names: Cell death inhibitors - OptiKira; ERN1 protein inhibitors - OptiKira; Small molecule therapeutics - OptiKira

Latest Information Update: 23 May 2018

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At a glance

  • Originator OptiKira
  • Developer Charles River Laboratories; OptiKira
  • Class Antihyperglycaemics; Eye disorder therapies; Neuroprotectants; Small molecules
  • Mechanism of Action Cell death inhibitors; ERN1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Amyotrophic lateral sclerosis; Diabetes mellitus; Retinitis pigmentosa

Most Recent Events

  • 17 May 2018 Preclinical trials in Amyotrophic lateral sclerosis in USA (Parenteral)
  • 02 Feb 2015 OptiKira licenses technology from University of California at San Francisco and the University of Washington
  • 02 Feb 2015 OptiKira has patents for kinase-inhibiting RNase attenuators in USA
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