ALRN 6924

Drug Profile

ALRN 6924

Alternative Names: ALRN-6924

Latest Information Update: 12 Apr 2018

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At a glance

  • Originator Aileron Therapeutics; Roche
  • Developer Aileron Therapeutics
  • Class Antineoplastics; Peptides
  • Mechanism of Action Proto-oncogene protein c mdm2 inhibitors; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haematological malignancies; Solid tumours
  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 11 Apr 2018 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia released by Aileron Therapeutics
  • 04 Apr 2018 Interim efficacy data from a phase I/Ib trial in Acute myeloid leukaemia and Myelodysplastic syndromes released by Aileron Therapeutics
  • 02 Apr 2018 Interim efficacy data from a phase I trial in Solid tumours and Haematological malignancies released by Aileron Therapeutics
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