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Nanvuranlat - J-Pharma

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Drug Profile

Nanvuranlat - J-Pharma

Alternative Names: JPH-203; JPH-203SBECD; KYT-0353

Latest Information Update: 24 Jun 2026

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At a glance

  • Originator J-Pharma
  • Class Amines; Antifibrotics; Antineoplastics; Benzoxazoles; Chlorobenzenes; Phenyl ethers; Small molecules
  • Mechanism of Action Amino acid transport system L inhibitors; Apoptosis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Biliary cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Biliary cancer
  • Phase II Colorectal cancer
  • Preclinical Idiopathic pulmonary fibrosis

Most Recent Events

  • 18 May 2026 Pharmacodynamics data from a preclinical trial in Solid tumours released by J-Pharma
  • 01 May 2026 Phase-I clinical trials in Biliary cancer (Inoperable/Unresectable, Recurrent) in Japan (IV-infusion) (jRCT2031260086)
  • 01 Jan 2026 Phase-III clinical trials in Biliary cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater, Inoperable/Unresectable) in USA (IV-infusion) (NCT07265674)

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