Anti-CD19 chimeric antigen receptor T cell therapy - Cellular Biomedicine Group

Drug Profile

Anti-CD19 chimeric antigen receptor T cell therapy - Cellular Biomedicine Group

Alternative Names: Anti-CD19 CART cell therapy - Cellular Biomedicine Group; Anti-CD19 CART cells; C-CAR011; CD19 specific CART cells

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Chinese PLA General Hospital
  • Developer Cellular Biomedicine Group; Chinese PLA General Hospital
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Diffuse large B cell lymphoma; Follicular lymphoma; Leukaemia; Mantle-cell lymphoma
  • Phase I Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 01 Apr 2018 Peking Union Medical College Hospital, in collaboration with Cellular Biomedicine, plans a phase I trial for B-Cell Non-Hodgkin's lymphoma (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (NCT03483688)
  • 31 Oct 2017 Cellular Biomedicine and Peking University People's Hospital plan a clinical trial for Acute lymphoblastic leukaemia (In adolescents, In adults) in China (NCT03327285)
  • 03 Oct 2017 Cellular Biomedicine in collaboration with Tianjin Medical University Cancer Institute and Hospital plans a phase I trial for Non-Hodgkin's lymphoma (Second-line therapy or greater) (NCT03299738)
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