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PRV 3279

Drug Profile

PRV 3279

Alternative Names: Anti-CD32B-anti-CD79B-bispecific-monoclonal-antibody; CD32BxCD79B; MGD 010; PRV-3279

Latest Information Update: 06 May 2025

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At a glance

  • Originator MacroGenics
  • Developer Provention Bio
  • Class Anti-inflammatories; Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Fc gamma receptor IIA antagonists; Fc gamma receptor IIB antagonists; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Systemic lupus erythematosus
  • No development reported Autoimmune disorders

Most Recent Events

  • 25 Apr 2025 Provention Bio terminates a phase II trial in Systemic lupus erythematosus in USA, Puerto Rico, China (IV) due to change in strategy (NCT05087628)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Autoimmune-disorders in USA (IV)
  • 27 Apr 2023 Provention Bio has been acquired by Sanofi

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