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CM 24

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Drug Profile

CM 24

Alternative Names: CM-24; MK 6018

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator cCAM Biotherapeutics
  • Developer Bristol-Myers Squibb; cCAM Biotherapeutics; Purple Biotech
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD66 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adenocarcinoma
  • Phase I/II Pancreatic cancer; Solid tumours

Most Recent Events

  • 25 Apr 2025 Efficacy and adverse events data from a phase I/II trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 10 Mar 2025 Purple Biotech plans to initiate a phase IIb trial for CM 24 in second half of 2025
  • 30 Sep 2024 Purple Biotech completes phase I/II clinical trial in Pancreatic cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in Israel, Spain, USA (IV) (NCT04731467)

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