Drug Profile


Alternative Names: PLX R 18; PLX RAD

Latest Information Update: 07 Mar 2018

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At a glance

  • Originator Hadassah Medical School; Pluristem Therapeutics
  • Developer Case Western Reserve University; Fukushima Medical University; Hadassah Medical School; National Institute of Allergy and Infectious Diseases; Pluristem Therapeutics
  • Class Stem cell therapies
  • Mechanism of Action Bone marrow cell stimulants; Cell differentiation modulators; Cell replacements; Stem cell modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute radiation syndrome; Aplastic anaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase I Aplastic anaemia; Graft-versus-host disease
  • Preclinical Acute radiation syndrome

Most Recent Events

  • 27 Feb 2018 Pharmacodynamics data from a preclinical trial in Graft-versus-host disease released by Pluristem
  • 26 Oct 2017 Israel Ministry of Health approves IND application for PLX R18 in Graft versus host disease
  • 23 Oct 2017 Pluristem Therapeutics has patent protection for PLX R18 in European Union
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