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Emestedastat - Actinogen Medical

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Drug Profile

Emestedastat - Actinogen Medical

Alternative Names: UE-2343; Xanamem

Latest Information Update: 04 Jun 2026

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At a glance

  • Originator University of Edinburgh
  • Developer Actinogen Medical
  • Class Antidementias; Antidepressants; Azabicyclo compounds; Ketones; Pyrazoles; Pyrimidines; Small molecules; Thiophenes
  • Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Phase II Major depressive disorder
  • No development reported Fragile X syndrome

Most Recent Events

  • 28 May 2026 Actinogen announces intention to submit Marketing Authorization Application to European Medical Agency for Alzheimer's disease
  • 28 May 2026 Actinogen receives positive EMA scientific advice for Alzheimer’s disease program
  • 28 May 2026 Actinogen medical plans a pivotal phase III trial for Alzheimer's disease in multiple regions in mid 2027

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