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Emestedastat - Actinogen Medical

Drug Profile

Emestedastat - Actinogen Medical

Alternative Names: UE-2343; Xanamem

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator University of Edinburgh
  • Developer Actinogen Medical
  • Class Antidementias; Azabicyclo compounds; Ketones; Pyrazoles; Pyrimidines; Small molecules; Thiophenes
  • Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Phase II Major depressive disorder
  • Preclinical Fragile X syndrome

Most Recent Events

  • 30 Jun 2025 Actinogen Medical plans a Type-C meeting with the US FDA for Alzheimer's disease in second half of 2025
  • 30 Jun 2025 Actinogen medical plans a XanaMIA-DUR clinical trial for Alzheimer's disease in first quarter of 2026
  • 30 Apr 2025 Actinogen Medical completed a Type-C meeting with the US FDA for Major depressive disorder prior to April 2025

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