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UE 2343

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UE 2343

Alternative Names: UE-2343; Xanamem

Latest Information Update: 28 Aug 2024

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At a glance

  • Originator University of Edinburgh
  • Developer Actinogen Medical
  • Class Antidementias; Azabicyclo compounds; Ketones; Pyrazoles; Pyrimidines; Small molecules; Thiophenes
  • Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Major depressive disorder
  • Preclinical Fragile X syndrome

Most Recent Events

  • 27 Aug 2024 Updated efficacy data from a phase IIa XanaCIDD trial for Major depressive disorder released by Actinogen Medical
  • 12 Aug 2024 Efficacy and adverse events data from a phase IIa XanaCIDD trial in Major depressive disorder released by Actinogen Medical
  • 01 Jul 2024 Actinogen Medical completes a phase IIa XanaCIDD trial in Major depressive disorder (Treatment-experienced) in Australia and United Kingdom (PO) (NCT05657691)

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