GSK 2330811
Alternative Names: GSK-2330811Latest Information Update: 28 Jul 2023
At a glance
- Originator GlaxoSmithKline
- Class Anti-inflammatories; Antifibrotics; Monoclonal antibodies; Skin disorder therapies
- Mechanism of Action Oncostatin M inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Systemic scleroderma
Most Recent Events
- 03 Feb 2021 Discontinued - Phase-II for Systemic scleroderma (Adjunctive treatment) in Canada, USA, Netherlands, United Kingdom (SC) (GlaxoSmithKline pipeline, February 2021)
- 03 Dec 2020 GlaxoSmithKline terminates a phase II COSMIS trial in Crohn's disease (Treatment experienced) (SC), prior to enrolment because of internal sponsor's decision to terminate project in Crohn's disease due to potential narrow therapeutic window (NCT04151225)
- 05 Oct 2020 Phase II development is still ongoing for Systemic scleroderma (Adjunctive treatment) in United Kingdom (NCT03041025)