Research programme: TRAIL receptor 2 agonists - Genmab

Drug Profile

Research programme: TRAIL receptor 2 agonists - Genmab

Alternative Names: GEN 1029; Hx-DR5-01; Hx-DR5-01/05; Hx-DR5-05; iDD 004

Latest Information Update: 05 Jan 2018

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At a glance

  • Originator iDD Biotech
  • Developer Genmab; iDD Biotech; VU University Medical Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioma; Multiple myeloma; Solid tumours

Most Recent Events

  • 09 Dec 2017 Preclinical trials in Multiple myeloma in Netherlands (unspecified route) before December 2017
  • 09 Dec 2017 Pharmacodynamics data from a preclinical study in Multiple myeloma presented at the 59th Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem-2017)
  • 13 Jul 2016 Pharmacodynamics data from a preclinical study presented at the 107th Annual Meeting of the American Association for Cancer Research (AACR-2016)
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