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Doravirine/lamivudine/tenofovir disoproxil fumarate - Merck & Co

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Drug Profile

Doravirine/lamivudine/tenofovir disoproxil fumarate - Merck & Co

Alternative Names: DELSTRIGO; DOR/3TC/TDF; MK-1439/lamivudine/tenofovir disoproxil fumarate; MK-1439A

Latest Information Update: 09 Dec 2025

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At a glance

  • Originator Merck Sharp & Dohme
  • Developer Merck Sharp & Dohme; National Institute of Allergy and Infectious Diseases
  • Class Antiretrovirals; Deoxyribonucleosides; Dideoxynucleosides; Nitriles; Phosphonic acids; Purines; Pyridones; Pyrimidine nucleosides; Small molecules; Triazoles
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors; Nucleoside reverse transcriptase inhibitors; Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 09 Dec 2025 Launched for HIV-1 infections (In adolescents, In adults, Treatment-naive) in Norway, Finland, Denmark, Czech Republic, Poland, Netherlands, Hungary, Israel, Austria, Sweden, Sweden, Ireland, Greece, Germany, France, Belgium (PO), prior to December 2025
  • 09 Dec 2025 Launched for HIV-1 infections in Russia, United Kingdom, Israel, Hong Kong, Argentina (PO), prior to December 2025
  • 27 Jan 2025 Merck Sharp & Dohme initiates enrolment in the phase-III ELDORADO trial for HIV-1 infections (Treatment-naive) in France (PO) (NCT06203132)

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