Belvarafenib - Hanmi Pharmaceutical
Alternative Names: GDC 5573; HM-95573; RG 6185Latest Information Update: 02 Jul 2024
At a glance
- Originator Hanmi Pharmaceutical
- Class Amides; Antineoplastics; Pyrimidines; Small molecules
- Mechanism of Action Proto oncogene protein c raf inhibitors; Proto-oncogene protein b-raf inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Solid tumours
- Phase I Malignant melanoma
Most Recent Events
- 31 May 2024 Efficacy and adverse event data from the phase II TAPISTRY trial in Solid tumors presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
- 24 Apr 2024 Genentech terminates its licensing agreement with Hanmi Pharmaceutical for the development and commercialisation of belvarafenib (Roche pipeline, May 2024)
- 15 Feb 2024 Belvarafenib is still in phase-I trials for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease) in South Korea (Roche pipeline, February 2024), (NCT03284502)