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Tislelizumab - BeiGene

Drug Profile

Tislelizumab - BeiGene

Alternative Names: BGB-A317; TEVIMBRA; Tilelizumab; Tirelizumab - BeiGene; Tizveni; VDT-482

Latest Information Update: 13 Jul 2024

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At a glance

  • Originator BeiGene
  • Developer Asieris Pharmaceuticals; BeiGene; Celgene Corporation; HUTCHMED; Leap Therapeutics; Novartis; Tianjin Medical University
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Squamous cell cancer; Nasopharyngeal cancer; Liver cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hodgkin's disease; Liver cancer; Non-small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Registered Gastric cancer; Nasopharyngeal cancer
  • Preregistration Oesophageal cancer; Small cell lung cancer
  • Phase III Cancer
  • Phase II Bladder cancer; Cervical cancer; Colorectal cancer; Lung cancer; Lymphoma; Rectal cancer
  • Phase I/II Endometrial cancer; Haematological malignancies; Triple negative breast cancer
  • No development reported Ovarian cancer; Renal cancer

Most Recent Events

  • 31 May 2024 Adverse events and efficacy data from phase II trial in Colorectal cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 31 May 2024 BeiGene completes enrolment in a phase II trial for Colorectal cancer (Neo-adjuvant therapy) in China (IV) (NCT05116085)
  • 31 May 2024 Efficacy and adverse events data from a phase I trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
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