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Anti-EGFR CAR-transduced T-cell therapy - AbelZeta Pharma

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Drug Profile

Anti-EGFR CAR-transduced T-cell therapy - AbelZeta Pharma

Alternative Names: Anti-EGFR CAR; CART-EGFR; CART-HER1; Chimeric-EGFR-antigen-receptor-modified-T-cells

Latest Information Update: 27 Nov 2023

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At a glance

  • Originator Chinese PLA General Hospital
  • Developer AbelZeta Pharma; Chinese PLA General Hospital
  • Class Cancer vaccines; CAR-T cell therapies; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 20 Nov 2023 Cellular Biomedicine Group is now called AbelZeta Pharma
  • 21 Aug 2017 Phase-I/II development is ongoing in China (NCT01869166)
  • 28 Sep 2015 Interim efficacy and adverse events data from a phase I/II trial in Solid tumours released by Cellular Biomedicine Group

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