APN 401

Drug Profile

APN 401

Alternative Names: APN-401; siRNA-transfected PBMC APN401; siRNA-transfected peripheral blood mononuclear cells - Apeiron

Latest Information Update: 05 Jul 2018

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At a glance

  • Originator Apeiron Biologics
  • Class Antineoplastics; Cell therapies; Small interfering RNA
  • Mechanism of Action CBLB protein expression inhibitors; RNA interference; Ubiquitin-protein ligase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 29 Jun 2018 Apeiron Biologics in-licenses technology targeting Cbl-b from Austrian Academy of Sciences and the Medical University of Vienna worldwide
  • 01 Jun 2018 Interim efficacy, adverse events and pharmacodynamics data from a phase I trial in Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 05 Mar 2018 Phase-II clinical trials in Solid tumours in USA (IV) (Apeiron pipeline, March 2018)
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