APN 401

Drug Profile

APN 401

Alternative Names: APN401; siRNA-transfected PBMC APN401; siRNA-transfected peripheral blood mononuclear cells - Apeiron

Latest Information Update: 05 Mar 2018

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At a glance

  • Originator Apeiron Biologics
  • Class Antineoplastics; Cell therapies; Small interfering RNA
  • Mechanism of Action CBLB protein expression inhibitors; RNA interference; Ubiquitin-protein ligase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 05 Mar 2018 Phase-II clinical trials in Solid tumours in USA (IV) (Apeiron pipeline, March 2018)
  • 05 Mar 2018 Apeiron Biologics plans a phase II trial for Pancreatic cancer (Apeiron website, March 2018)
  • 28 Jan 2018 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in USA (IV, Infusion)
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