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Irsenontrine - Eisai Inc

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Drug Profile

Irsenontrine - Eisai Inc

Alternative Names: [14C] E 2027; E 2027; E2027 maleate; ER-000592221-MAL; ER-592221-12; Irsenontrine maleate

Latest Information Update: 30 Sep 2024

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At a glance

  • Originator Eisai Inc
  • Class 3-ring heterocyclic compounds; Antidementias; Ethers; Furans; Neuroprotectants; Pyrazoles; Pyridines; Quinolines
  • Mechanism of Action Phosphodiesterase 9A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Lewy body disease
  • Phase II Dementia

Most Recent Events

  • 28 Jul 2024 Efficacy data from phase II/III DELPHIA trial in Lewy Body disease presented at the Alzheimer's Association International Conference (AAIC-2024)
  • 27 Jan 2022 Eisai completes a phase II trial for Lewy Body disease (In adults, In the elderly) in USA and Canada (NCT04764669)
  • 18 Mar 2021 Chemical structure information added

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