Research programme: neurodegenerative diseases diagnostics and therapeutics - AC Immune

Drug Profile

Research programme: neurodegenerative diseases diagnostics and therapeutics - AC Immune

Alternative Names: a-syn-PET imaging agent - AC Immune; Alpha-synuclein inhibitors - AC Immune; Alpha-synuclein-PET based diagnostics and therapeutics - AC Immune; Anti-TDP-43 antibody; Morphomer Tau; Morphomer α-syn inhibitors - AC Immune; Tau Morphomer; Tau-PET imaging agent - AC Immune

Latest Information Update: 28 Mar 2018

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At a glance

  • Originator AC Immune
  • Developer AC Immune; Biogen
  • Class Antibodies; Antidementias; Imaging agents; Radiopharmaceutical diagnostics; Small molecules
  • Mechanism of Action Alpha-synuclein inhibitors; Positron-emission tomography enhancers; Tau protein inhibitors; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease
  • Research Dementia; Parkinson's disease; Unspecified

Most Recent Events

  • 05 Apr 2018 AC Immune plans a phase I trial for Tau Morphomer for Alzheimer's disease by end of 2018
  • 20 Mar 2018 Early research in Undefined indication in Switzerland (unspecified route)
  • 15 Mar 2018 AC Immune plan to initiate clinical studies for the PET tracer programme in the second half of 2018
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