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Firsocostat - Gilead Sciences

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Drug Profile

Firsocostat - Gilead Sciences

Alternative Names: GS-0976; NDI 010976

Latest Information Update: 03 Jan 2023

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At a glance

  • Originator Nimbus Therapeutics
  • Developer Gilead Sciences; Nimbus Therapeutics
  • Class Anti-inflammatories; Hepatoprotectants; Propionic acids; Pyridines; Small molecules
  • Mechanism of Action Acetyl-CoA carboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis

Most Recent Events

  • 04 Nov 2022 Pharmacodynamics data from a phase II ATLAS trial in Nonalcoholic steatohepatitis presented at the 73rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2022)
  • 28 Aug 2022 No recent reports of development identified for phase-I development in Non-alcoholic-steatohepatitis(In volunteers) in Germany (PO, Tablet)
  • 28 Aug 2022 No recent reports of development identified for phase-I development in Non-alcoholic-steatohepatitis(In volunteers) in Romania (PO, Tablet)

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