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Research programme: hypoxia inducible factor-proline dioxygenase inhibitors - Akebia Therapeutics

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Drug Profile

Research programme: hypoxia inducible factor-proline dioxygenase inhibitors - Akebia Therapeutics

Alternative Names: AKB-6899; HIF-PH inhibitors - Akebia Therapeutics

Latest Information Update: 21 Mar 2023

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At a glance

  • Originator Akebia Therapeutics
  • Class Anti-inflammatories; Antineoplastics; Eye disorder therapies; Small molecules
  • Mechanism of Action Hypoxia-inducible factor-proline dioxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute kidney injury; Retinopathy of prematurity
  • Discontinued Cancer; Inflammatory bowel diseases

Most Recent Events

  • 10 Mar 2023 Discontinued - Preclinical for Cancer in USA (unspecified route)
  • 10 Mar 2023 Discontinued - Preclinical for Inflammatory bowel diseases in USA (unspecified route)
  • 10 Mar 2023 Preclinical trials in Acute kidney injury and Retinopathy of prematurity in USA (unspecified route) as of March 2023

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