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Cytomegalovirus vaccine (Triplex) - Helocyte

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Drug Profile

Cytomegalovirus vaccine (Triplex) - Helocyte

Alternative Names: CMV-MVA triplex vaccine; Cytomegalovirus modified vaccinia Ankara triplex vaccine; Cytomegalovirus specific T-cells Triplex; Multi-CMV epitope modified vaccinia Ankara vaccine - Helocyte; MVA multi CMV epitopes; MVA-CMV-Triplex; Triplex

Latest Information Update: 07 Aug 2025

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At a glance

  • Originator City of Hope National Medical Center
  • Developer City of Hope National Medical Center; Helocyte
  • Class Cytomegalovirus vaccines; Gene therapies; Immunotherapies; Peptide vaccines; T lymphocyte cell therapies; Viral vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Cytomegalovirus infections
  • Phase I Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 12 Mar 2025 Phase-I clinical trials in Precursor B-cell lymphoblastic leukaemia-lymphoma (Combination therapy) in USA (IM) (NCT06735690)
  • 13 Aug 2024 Fortress Biotech completes enrolment in its phase-II trial for Cytomegalovirus infections (Prevention) in USA prior to August 2024 (IM), (NCT05099965)
  • 30 Apr 2024 City of Hope Medical Center initiates a phase II trial in Hematopoietic stem cell transplant (Prevention) in USA (IM) (NCT06059391)

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