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RT 100

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Drug Profile

RT 100

Alternative Names: Ad5-AC6; Ad5.hAC6; Adenylate cyclase gene therapy - Renova; RT100

Latest Information Update: 05 Oct 2020

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At a glance

  • Originator Renova Therapeutics
  • Class Gene therapies
  • Mechanism of Action Adenylate cyclase expression stimulants; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Heart failure

Most Recent Events

  • 05 Oct 2020 Phase II development for Heart failure is still ongoing in USA (Renova Therapeutics pipeline, September 2020)
  • 05 Jun 2019 Renova Therapeutics withdraws the phase III FLOURISH trial for Heart failure in USA due to the clinical development plans and strategy for RT 100 being re-evaluated (Intracoronary) (NCT03360448)
  • 19 Dec 2017 RT 100 receives Fast Track designation for Heart failure [Intracoronary] in USA

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