Encochleated amphotericin B - Matinas BioPharma

Drug Profile

Encochleated amphotericin B - Matinas BioPharma

Alternative Names: CAmB; MAT 2203

Latest Information Update: 20 Jul 2018

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At a glance

  • Originator Aquarius Biotechnologies
  • Developer Aquarius Biotechnologies; Matinas BioPharma
  • Class Antifungals; Antiprotozoals; Macrolides
  • Mechanism of Action Cell membrane permeability enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Candidiasis; Mycoses; Vulvovaginal candidiasis
  • Preclinical Aspergillosis; Cryptococcosis; Visceral leishmaniasis

Most Recent Events

  • 20 Jul 2018 Pharmacodynamics data from a preclinical trials in Candidiasis presented at the ASM Microbe 2018 (AASM-2018)
  • 06 Jun 2018 Matinas BioPharma plans a pivotal phase II trial for prevention of Mycoses (in patients with Acute myeloid leukaemia and Acute lymphoblastic leukaemia) in the first half of 2019 (NCT03187691)
  • 16 Mar 2018 Matinas BioPharma plans a phase II trial for Candidiasis in first half of 2019
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