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Gallium-68 NOTA AE105 - Curasight

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Drug Profile

Gallium-68 NOTA AE105 - Curasight

Alternative Names: 68Ga-NOTA-AE105; 68Ga-NOTA-Asp-Cha-Phe-Ser-Arg-Tyr-Leu-Trp-Ser; CS 001; uTRACE; uTREAT

Latest Information Update: 22 Jan 2026

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At a glance

  • Originator Curasight
  • Developer Curasight; Rigshospitalet
  • Class Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters; Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bladder cancer; Breast cancer; Glioblastoma; Gynaecological cancer; Head and neck cancer; Mesothelioma; Neuroendocrine tumours; Non-small cell lung cancer; Oropharyngeal cancer; Prostate cancer
  • Phase I Brain cancer

Most Recent Events

  • 12 Jan 2026 Efficacy and pharmacokinetics data from a phase I trial in Glioblastoma (Diagnosis) released by Curasight
  • 18 Dec 2025 Phase-I clinical trials in Brain cancer in European Union (IV)
  • 26 Aug 2025 Curasight plans a phase I trial for Cancer (Diagnosis) in Europe (IV) by the end of 2025

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