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Gallium-68 NOTA AE105 - Curasight

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Drug Profile

Gallium-68 NOTA AE105 - Curasight

Alternative Names: 68Ga-NOTA-AE105; 68Ga-NOTA-Asp-Cha-Phe-Ser-Arg-Tyr-Leu-Trp-Ser; CS 001; uTRACE; uTREAT

Latest Information Update: 15 Feb 2024

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At a glance

  • Originator Curasight
  • Developer Curasight; Rigshospitalet
  • Class Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters; Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bladder cancer; Breast cancer; Glioblastoma; Gynaecological cancer; Head and neck cancer; Mesothelioma; Neuroendocrine tumours; Non-small cell lung cancer; Oropharyngeal cancer; Prostate cancer

Most Recent Events

  • 13 Feb 2024 Curasight plans a phase I/II basket trial for Glioblastoma, Neuroendocrine tumors, Head and neck cancer, Non-small cell lung cancer and pancreatic cancer in the beginning of 2025
  • 29 Jun 2023 Preclinical trials in Glioblastoma in Denmark prior to June 2023 (IV)
  • 29 Jun 2023 Interim efficacy data from a phase-II trial in Glioblastoma (Diagnosis) released by Curasight (IV)

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