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Recombinant alpha Crystallin B - Serenity Bioworks

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Drug Profile

Recombinant alpha Crystallin B - Serenity Bioworks

Alternative Names: CRYAB; DC TAB; HspB5; Recombinant human alpha B-crystallin - Delta Crystallon; Recombinant human CRYAB - Delta Crystallon; SER-101 - Serenity Bioworks

Latest Information Update: 29 Apr 2022

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At a glance

  • Originator Delta Crystallon
  • Developer Delta Crystallon; Serenity Bioworks
  • Class Alpha crystallins; Recombinant proteins; Urologics
  • Mechanism of Action Alpha-crystallin B chain replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Lupus nephritis
  • Discontinued Amyotrophic lateral sclerosis; Multiple sclerosis; Progressive supranuclear palsy

Most Recent Events

  • 29 Apr 2022 Discontinued - Phase-I for Progressive supranuclear palsy in Netherlands (IV)
  • 29 Apr 2022 Discontinued - Phase-II for Multiple sclerosis in Bulgaria (IV)
  • 28 Apr 2022 Serenity Bioworks acquires Recombinant alpha Crystallin B from Delta Crystallon
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