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Belzupacap sarotalocan - Aura Biosciences/National Cancer Institute

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Drug Profile

Belzupacap sarotalocan - Aura Biosciences/National Cancer Institute

Alternative Names: AU 011; Bel-sar; Belzupacap serotalocan; Light-activated AU-011

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Aura Biosciences; National Cancer Institute (USA)
  • Developer Aura Biosciences
  • Class Antineoplastics; Drug conjugates; Phthalocyanines; Viral proteins
  • Mechanism of Action Cell death stimulants; Photosensitisers; Reactive oxygen species stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Uveal melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Uveal melanoma
  • Phase I/II Bladder cancer
  • Preclinical Solid tumours

Most Recent Events

  • 28 Oct 2025 No recent reports of development identified for phase-I development in Bladder-cancer in USA (Intratumoural, Injection)
  • 15 May 2025 Aura Biosciences files for patent protection with US PTO for Belzupacap sarotalocan in USA
  • 15 May 2025 Phase-I/II clinical trials in Bladder cancer (Intratumoural)

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