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SPR 206

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Drug Profile

SPR 206

Alternative Names: EVER-206; SPR-206

Latest Information Update: 22 Oct 2025

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At a glance

  • Originator Northern Antibiotics
  • Developer Everest Medicines; Evotec SE; Spero Therapeutics
  • Class Amides; Amines; Anti-infectives; Antibacterials; Benzene derivatives; Chlorinated hydrocarbons; Polymixins
  • Mechanism of Action Bacterial outer membrane protein modulators; Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gram-negative infections; Nosocomial pneumonia; Ventilator associated pneumonia

Most Recent Events

  • 11 Apr 2025 Antimicrobial data from preclinical trial in Gram negative infections presented at the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID-2025)
  • 27 Mar 2025 Discontinued - Phase-I for Gram-negative infections (In volunteers) in Australia (IV)
  • 27 Mar 2025 Discontinued - Phase-I for Gram-negative infections (In volunteers) in China (IV)

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