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Alternative Names:
Lademirsen sodium; RG 012; RG 456070; SAR 339375
Latest Information Update: 21 Oct 2020
Price :
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At a glance
Originator
Regulus Therapeutics; Sanofi
Developer
Regulus Therapeutics
Class
Antisense oligoribonucleotides; MicroRNAs; Urologics
Mechanism of Action
MicroRNA inhibitors; RNA interference
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Hereditary nephritis
New Molecular Entity
Yes
Highest Development Phases
Phase II
Hereditary nephritis
Most Recent Events
29 Sep 2020
Lademirsen is still in phase II trials for Hereditary nephritis in USA and United Kingdom (SC) (NCT02855268)
13 Nov 2019
Sanofi plans to submit a regulatory application for Alport syndrome, in 2023 or later
04 Nov 2019
Sanofi and Regulus Therapeutics reinitiate patient enrolment in the phase II HERA trial in Hereditary nephritis in USA and United Kingdom (SC) (NCT02855268)
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