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SEL 212

Drug Profile

SEL 212

Alternative Names: Non-immunogenic uricase; Pegadricase-SVP; Pegsiticase-SVP; SEL-037/SEL-110; SEL-212; SEL-212A; SEL-212B; SVP-Rapamycin/pegsiticase

Latest Information Update: 09 Jul 2024

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At a glance

  • Originator Selecta Biosciences
  • Developer Cartesian Therapeutics
  • Class Antigouts; Enzymes; Oxidoreductases; Polyethylene glycols; Recombinant proteins
  • Mechanism of Action Urate oxidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preregistration Gout

Most Recent Events

  • 02 Jul 2024 Preregistration for Gout (Combination therapy, Treatment-experienced) in USA (IV)
  • 31 Mar 2024 SEL 212 receives fast track designation for Gout in USA
  • 10 Nov 2023 Pooled analysis of adverse events and efficacy data from a phase III DISSOLVE trials in Gout presented at the ACR convergence 2023 (ACR-2023)
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