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Izencitinib - Theravance Biopharma

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Drug Profile

Izencitinib - Theravance Biopharma

Alternative Names: JNJ-8398; TD 1473

Latest Information Update: 23 Aug 2023

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At a glance

  • Originator Theravance Biopharma
  • Developer Mayo Clinic; Theravance Biopharma
  • Class Amines; Anti-inflammatories; Azabicyclo compounds; Gastrokinetics; Naphthyridines; Nitriles; Pyrazoles; Small molecules
  • Mechanism of Action Janus kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Crohn's disease; Diabetic gastroparesis; Inflammatory bowel diseases; Ulcerative colitis

Most Recent Events

  • 31 Dec 2022 Discontinued - Phase-I for Inflammatory bowel diseases (In volunteers) in USA (PO)
  • 31 Dec 2022 Discontinued - Phase-I for Ulcerative colitis (In volunteers) in USA (IV)
  • 31 Dec 2022 Discontinued - Phase-II for Crohn's disease in USA (PO)

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